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Table 1 Subjects’ demographics, n = 12 subjects

From: Airway fibrin formation cascade in allergic asthma exacerbation: implications for inflammation and remodeling

Subject

Age

SBP-Ag

FEV1 (%)

Total BAL cells (10E4 Cells/mL)

EOS (%)

EOS Change (%)

Post–Pre

PMN (%)

PMN Change (%)

Post–Pre

LYM (%)

LYM Change (%)

Post–Pre

MAC (%)

MAC Change (%)

Post–Pre

FeNO

1

23

Pre

75

14.8

1.1

 

1

 

3.6

 

94.3

 

56

Post

 

145.4

74.5

73.4

4.8

3.8

6.9

3.3

13.8

− 80.5

82

2

27

Pre

102

10.4

0.4

 

0.2

 

2.5

 

96.9

 

19.9

Post

 

233.7

73

72.6

1.9

1.7

2

-0.5

23.1

− 73.8

30.1

3

31

Pre

135

7.7

0.5

 

1

 

4.8

 

93.7

 

41.4

Post

 

17.9

51.7

51.2

5

4

7

2.2

36.3

− 57.4

59.8

4

36

Pre

87

8.9

0.4

 

0.1

 

4.8

 

94.7

 

77.1

Post

 

68.3

72

71.6

1.9

1.8

6.8

2

20.2

− 74.5

66.3

5

21

Pre

83

11.1

0.2

 

0.4

 

7.2

 

92.2

 

49.9

Post

 

76.5

77.2

77

1.7

1.3

3

-4.2

18.1

− 74.1

66.8

6

27

Pre

95

7.1

0.4

 

1.2

 

8.6

 

89.8

 

40.4

Post

 

221.7

71.3

70.9

3.2

2

6.6

-2

18.9

− 70.9

57.1

7

27

Pre

71

6.4

1

 

1.8

 

14.5

 

82.7

 

47.9

Post

 

90.7

66.3

65.3

5.4

3.6

8.6

-5.9

19.7

− 63

57

8

19

Pre

103

12.5

0.6

 

0.9

 

5.3

 

93.2

 

24.5

Post

 

193.7

80.6

80

1

0.1

4.8

-0.5

13.6

− 79.6

69.2

9

22

Pre

108

38

0.2

 

0.7

 

32.2

 

66.9

 

23

Post

 

542.6

72.7

72.5

3.6

2.9

14.2

-18

9.5

− 57.4

52.5

10

27

Pre

83

11.3

ND

 

ND

 

ND

 

ND

 

28.7

Post

 

12.2

17.7

ND

9

ND

12.4

ND

60.9

ND

55.6

11

20

Pre

100

8.6

0.6

 

0.7

 

8.8

 

89.9

 

49.4

Post

 

263.5

77.8

77.2

1.4

0.7

12.2

3.4

9.6

− 80.3

99.3

12

33

Pre

99

9.1

ND

 

ND

 

ND

 

ND

 

ND

Post

 

16.3

29.9

ND

2.1

ND

10.6

ND

57.4

ND

ND

  1. Pre  pre-segmental bronchoprovocation with an allergen (SBP-Ag), Post  48 h post-SBP-Ag, FEV1 (%)  forced exhaled volume in 1 s as % predicted obtained prealbutarol and pre-allergen challenge, EOS (%)  percentage of eosinophils in BAL fluid, PMN (%)  percentage of neutrophils in BAL fluid, LYM (%)  percentage of lymphocytes in BAL fluid, MAC (%) percentage of macrophages in BAL fluid, FeNO  fractional exhaled nitric oxide, ND  not determined