Fig. 3
From: Elevated level of multibranched complex glycan reveals an allergic tolerance status
Comparison of statistically significant relative intensities between the allergic patients treated without AIT and the allergic patients treated with AIT who had just entered the maintenance phase (a) and the allergic patients treated with AIT who had been in the maintenance phase over 1 year (b). The 84 most intense peaks were compared, and only statistically significant peaks are shown (*p < 0.01; **p < 0.05; *** p < 0.001; multiple testing correction was conducted: **** p < 0.05/84). The levels of nine N-glycans were changed constantly at two time points after AIT. The relative intensities of the nine N-glycans (c); Heatmap made by logging the relative intensities of these nine N-glycan chains in 57 patients with a base of 10 (d). Without AIT: patients were not treated with AIT; Time 1 after treatment: patients were treated with AIT and had just entered the maintenance phase; Time 2 after treatment: patients were treated with AIT and had been in the maintenance phase for 1 year. All cartoons described the possible structure matching the composition (other structure possibilities are not excluded)