Table 2 Differential expression of top 10 downregulated proteins in the mCRC and CRC groups
From: Proteomic analysis of plasma exosomes in patients with metastatic colorectal cancer
No. | Accession | GeneSymbol | Description | mCRC/CRC ratio | P-value |
|---|---|---|---|---|---|
1 | P28062 | PSMB8 | Proteasome subunit beta type-8 OS = Homo sapiens OX = 9606 GN = PSMB8 PE = 1 SV = 3 | 0.806 | 0.046 |
2 | P06239 | LCK | Tyrosine-protein kinase Lck OS = Homo sapiens OX = 9606 GN = LCK PE = 1 SV = 6 | 0.690 | 0.017 |
3 | Q15286 | RAB35 | Ras-related protein Rab-35 OS = Homo sapiens OX = 9606 GN = RAB35 PE = 1 SV = 1 | 0.685 | 0.014 |
4 | P28070 | PSMB4 | Proteasome subunit beta type-4 OS = Homo sapiens OX = 9606 GN = PSMB4 PE = 1 SV = 4 | 0.685 | 0.039 |
5 | P60033 | CD81 | CD81 antigen OS = Homo sapiens OX = 9606 GN = CD81 PE = 1 SV = 1 | 0.669 | 0.025 |
6 | P08962 | CD63 | CD63 antigen OS = Homo sapiens OX = 9606 GN = CD63 PE = 1 SV = 2 | 0.643 | 0.015 |
7 | Q9H4G4 | GLIPR2 | Golgi-associated plant pathogenesis-related protein 1 OS = Homo sapiens OX = 9606 GN = GLIPR2 PE = 1 SV = 3 | 0.625 | 0.022 |
8 | P61224 | RAP1B | Ras-related protein Rap-1b OS = Homo sapiens OX = 9606 GN = RAP1B PE = 1 SV = 1 | 0.620 | 0.010 |
9 | Q15771 | RAB30 | Ras-related protein Rab-30 OS = Homo sapiens OX = 9606 GN = RAB30 PE = 1 SV = 2 | 0.608 | 0.018 |
10 | P23141 | CES1 | Liver carboxylesterase 1 OS = Homo sapiens OX = 9606 GN = CES1 PE = 1 SV = 2 | 0.605 | 0.024 |