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Table 1 Patient characteristics

From: ARTN and CCL23 predicted chemosensitivity in acute myeloid leukemia: an Olink® proteomics approach

 

All patients

(n = 43)

Non-CR group

(n = 14)

CR group

(n = 29)

p

Age, y (mean ± SD)

51.1 ± 11.7

51.8 ± 13.4

50.7 ± 11.0

0.784a

Sex (n, %)

    

 Male

24 (55.8)

9 (64.3)

15 (51.7)

0.523c

 Female

19 (44.2)

5 (35.7)

14 (48.3)

 

Leukocytes, 103/µL (mean ± SD)

63.4 ± 71.4

46.5 ± 55.2

71.0 ± 77.2

0.235a

Blasts in marrow, % (mean ± SD)

54.3 ± 21.7

60.7 ± 20.1

51.3 ± 22.2

0.184a

Blasts in PB, % (mean ± SD)

32.3 ± 28.3

33.7 ± 25.3

31.6 ± 30.1

0.821a

FAB classification (n, %)

    

 M0

2 (4.7)

1 (7.1)

1 (3.4)

0.585b

 M1

2 (4.7)

1 (7.1)

1 (3.4)

 

 M2

23 (53.5)

8 (57.2)

15 (51.8)

 

 M4

10 (23.2)

2 (14.4)

8 (27.6)

 

 M5

5 (11.6)

1 (7.1)

4 (13.8)

 

 M6

1 (2.3)

1 (7.1)

0 (0.0)

 

Cytogenetics (n, %)

    

 Favorable

5 (11.6)

0 (0.0)

5 (17.2)

0.098b

 Intermediate

19 (44.2)

5 (35.7)

14 (48.3)

 

 Unfavorable

19 (44.2)

9 (64.3)

10 (34.5)

 

Molecular mutation (n, %)

    

 FLT3 ITD mutation

6 (14.0)

1 (7.1)

5 (17.2)

0.645c

 NPM1 mutation

9 (20.9)

0 (0.0)

9 (31.0)

0.020c

  1. CR: complete remission; SD: standard deviation; PB: peripheral blood; FAB: French-America-British
  2. Data were compared using Independent a Sample t test, b chi-square test, c Fisher’s exact test