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  2. With the rapid development of mass spectrometry-based technologies such as multiple reaction monitoring and heavy-isotope-labeled-peptide standards, quantitative analysis of biomarker proteins using mass spect...

    Authors: Yan Li, Lori J. Sokoll, Peter E. Barker, Hui Zhang and Daniel W. Chan
    Citation: Clinical Proteomics 2008 4:9011
    Content type: Article Published on:

  3. A novel approach of ion mobility tandem mass spectrometry (IMS-MS/MS) is applied to analysis of human glycourinome to obtain carbohydrate pattern data of congenital disorders of glycosylation patient. Overlapp...

    Authors: Sergey Y. Vakhrushev, James Langridge, Iain Campuzano, Chris Hughes and Jasna Peter-Katalinić
    Citation: Clinical Proteomics 2008 4:9010
    Content type: Articles Published on:

  4. Glycoproteomics is undergoing rapid development, largely as a result of advances in technologies for isolating glycoproteins and analyzing glycan structures. However, given the number and diversity of glycans,...

    Authors: David W. Ralin, Shane C. Dultz, Judd E. Silver, Jeffrey C. Travis, Majlinda Kullolli, William S. Hancock and Marina Hincapie
    Citation: Clinical Proteomics 2008 4:9007
    Content type: Articles Published on:

  5. Glycosylations range among the most common posttranslational modifications with an estimated 50% of all proteins supposed to be glycosylated. These modifications are required for essential cellular processes i...

    Authors: Urs Lewandrowski, Katharina Lohrig, René P. Zahedi, Dirk Wolters and Albert Sickmann
    Citation: Clinical Proteomics 2008 4:9006
    Content type: Article Published on:

  6. This study established two-dimensional gel electrophoresis (2-DE) profiles for human well-differentiated laryngeal squamous cell carcinoma tissue and paired normal mucosa epithelia tissue and identified protei...

    Authors: Jian-rong Zhou, Zhong-xue Fu, Jie Li, Lian-zhi Wei and Jun-cai Li
    Citation: Clinical Proteomics 2008 3:9009
    Content type: Article Published on:

  10. The collection of lung fluid using a suction catheter (s-Cath) and non-bronchoscopic bronchoalveolar lavage (mini-BAL) are two minimally invasive methods of sampling the distal airspaces in patients with the a...

    Authors: Dong W. Chang, Giuseppe Colucci, Tomas Vaisar, Trevor King, Shinichi Hayashi, Gustavo Matute-Bello, Roger Bumgarner, Jay Heinecke, Thomas R. Martin and Guido M. Domenighetti
    Citation: Clinical Proteomics 2008 3:9002
    Content type: Article Published on:

  11. The aim of this study was to evaluate a multiple immunoaffinity protein depletion (multiple affinity removal system, MARS) pre-treatment strategy with subsequent two-dimensional polyacrylamide gel electrophore...

    Authors: Karen T. Oliva, Mustafa Ayhan, Gillian Barker, Nicole L. Dellios, Michael A. Quinn and Gregory E. Rice
    Citation: Clinical Proteomics 2007 3:9001
    Content type: Article Published on:

  12. In recent years, differential analysis of proteins from human saliva, i.e., proteomic analysis, has received much attention mainly due to its unstressful sampling and its great potential for biomarker research...

    Authors: François Chevalier, Christophe Hirtz, Sandrine Chay, Frédéric Cuisinier, Nicolas Sommerer, Michel Rossignol and Dominique Deville de Périère
    Citation: Clinical Proteomics 2007 3:9000
    Content type: Article Published on:

  14. The aim of this study was to examine the protein expression profiles of persistentChlamydia pneumoniae by two-dimensional polyacrylamide gel electrophoresis (2D PAGE) and surface-enhanced laser desorption ionizat...

    Authors: Sanghamitra Mukhopadhyay, Saeed A. Jortani, Roland Valdes, Christine Q. Simmons, Erin D. Sullivan, Richard D. Miller and James T. Summersgill
    Citation: Clinical Proteomics 2006 2:BF02752501
    Content type: Original Article Published on:

  15. The proteins in blood were all first expressed as mRNAs from genes within cells. There are databases of human proteins that are known to be expressed as mRNA in human cells and tissues. Proteins identified fro...

    Authors: Peihong Zhu, Peter Bowden, Voitek Pendrak, Herbert Thiele, Du Zhang, Michael Siu, Eleftherios P. Diamandis and John Marshall
    Citation: Clinical Proteomics 2006 2:BF02752500
    Content type: Original Article Published on:

  16. Fetal growth restriction (FGR) affects 3–5% of pregnancies and is associated with increased perinatal morbidity and mortality. Currently, there is no reliable biochemical test to differentiate a pathological F...

    Authors: Madhulika B. Gupta, Maxim D. Seferovic, Suya Liu, Robert J. Gratton, Amanda Doherty-Kirby, Gilles A. Lajoie and Victor K. M. Han
    Citation: Clinical Proteomics 2006 2:BF02752499
    Content type: Original Article Published on:

  17. Epidemiological studies have shown that Asian populations display a lower incidence of hormone-dependant cancers, cardiovascular disease, osteoporosis, and menopausal ailments compared to Western societies. Av...

    Authors: Nicki Konstantakopoulos, Martin R. Larsen, Ian G. Campbell, Michael A. Quinn, Mark S. Baker, Harry M. Georgiou and Gregory E. Rice
    Citation: Clinical Proteomics 2006 2:BF02752498
    Content type: Original Article Published on:

  18. In this manuscript, we compared serum profiles obtained with two related technologies, SELDI-TOF and Clinprot, using a single bioinformatic algorithm. These two approaches rely on mass spectrometry to detect p...

    Authors: Christelle Reynès, Stéphane Roche, Laurent Tiers, Robert Sabatier, Patrick Jouin, Nicolas Molinari and Sylvain Lehmann
    Citation: Clinical Proteomics 2006 2:BF02752497
    Content type: Original Article Published on:

  19. Reversible phosphorylation is one of the most important posttranslational modifications of cellular proteins. Mass spectrometry is a widely used technique in the characterization of phosphorylated proteins and...

    Authors: Dongxia Wang, Philip A. Cole and Robert J. Cotter
    Citation: Clinical Proteomics 2006 2:BF02752496
    Content type: Original Article Published on:

  20. The future of cancer diagnostics will be based on a panel of proteomic biomarkers. They could be used to detect cancer at an early stage, to predict and to direct therapies. Enzymes and related proteins are im...

    Authors: Daniel W. Chan and Shu-Ling Liang
    Citation: Clinical Proteomics 2006 2:BF02752495
    Content type: Editorial Published on:

  21. Owing to its noninvasive collection, saliva is considered as a potent diagnostic fluid. The goal of this study was to investigate the modification of the salivary proteome occurring in type 1 diabetes to highl...

    Authors: Christophe Hirtz, François Chevalier, Nicolas Sommerer, Isabelle Raingeard, Jacques Bringer, Michel Rossignol and Dominique Deville de Périere
    Citation: Clinical Proteomics 2006 2:201117
    Content type: Original Article Published on:

  22. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF/MS) serves as a rapid and accurate means to determine masses of proteins independent of their shapes or interactions with...

    Authors: Glen L. Hortin and Alan T. Remaley
    Citation: Clinical Proteomics 2006 2:201103
    Content type: Original Article Published on:

  23. Recent studies have evaluated proper acquisition and storage procedures for the use of serum or plasma for mass spectrometry (MS)-based proteomics. The present study examines the proteome stability of human ce...

    Authors: Srikanth Ranganathan, Anna Polshyna, Georgina Nicholl, James Lyons-Weiler and Robert Bowser
    Citation: Clinical Proteomics 2006 2:20191
    Content type: Original Article Published on:

  24. There is a great desire to relate the patterns of endogenous peptides in blood to human disease and drug response. The best practices for the preparation of blood fluids for analysis are not clear and also rel...

    Authors: Declan Williams, Peihong Zhu, Peter Bowden, Catherine Stacey, Mike McDonell, Paul Kowalski, Jane Marie Kowalski, Ken Evans, Eleftherios P. Diamandis, K. W. Michael Siu and John Marshall
    Citation: Clinical Proteomics 2006 2:20167
    Content type: Original Article Published on:

  25. Despite many years of research efforts and continued progress in the identification of urine markers for detection of bladder cancer, none of the markers described to date has been able to replace cystoscopy a...

    Authors: Pavel Gromov, Josè M. A. Moreira, Irina Gromova and Julio E. Celis
    Citation: Clinical Proteomics 2006 2:20145
    Content type: Original Article Published on:

  27. Data mining application to proteomic data from mass spectrometry has gained much interest in recent years. Advances made in proteomics and mass spectrometry have resulted in considerable amount of data that ca...

    Authors: Asha Thomas, Georgia D. Tourassi, Adel S. Elmaghraby, Roland Valdes Jr. and Saeed A. Jortani
    Citation: Clinical Proteomics 2006 2:20113
    Content type: Original Article Published on:
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Clinical Proteomics

ISSN: 1559-0275